Description: We now seek for enthusiastic new colleagues to analyze the interplay between germline stem cells and their support cells under homeostatic and compromised cellular conditions. In particular, the project aims at identifying pathways monitoring genome integrity in stem cells and at uncovering the role of mitotic checkpoint components in monitoring asymmetric stem cell division in the male germline. The project builds on a wide array of advanced resources established in the Lohmann lab and will provide ample opportunity to implement and apply high-end techniques to investigate stem cells of the Drosophila male stem cell system at multiple scales. The Heidelberg Molecular Life Science Community offers a vibrant stem cell research community, as well as state-of-the-art core facilities. You will have the opportunity to closely collaborate with highly recognized stem cell researchers of the SFB873 and beyond.
Your Profile: Successful candidates will have experience in confocal microscopy, advanced immunohistochemistry and possibly in Drosophila genetics and molecular biology. The ability to quickly integrate into an interdisciplinary team and work independently within an academic research environment is essential. The position is immediately available, the salary is according to TV-L regulations. Disabled persons with comparable skills will be preferentially considered.
Applications should be sent to:
Prof. Ingrid Lohmann
University of Heidelberg
Centre for Organismal Studies (COS) Heidelberg
Department of Developmental Biology
Im Neuenheimer Feld 230
Ph: +49 (0)6221 545523
Fx: +49 (0)6221 546424
1. Papagiannouli F, Schardt L, Grajcarek J, Ha N and Lohmann I (2014). The Hox gene Abd-B controls stem cell niche function in the Drosophila testis.
Developmental Cell 28, 189-202.
2. Merabet S and Lohmann I (2015). Towards a new twist in Hox and TALE DNA-binding specificity. Developmental Cell 32(3):259-261.
3. Tamirisa S, Papagiannouli F, Rempel E, Ermakova O, Trost N, Zhou J, Mundorf J, Brunel S, Ruhland N, Boutros M, Lohmann JU and Lohmann I (2018). Decoding
the Regulatory Logic of the Drosophila Male Stem Cell System. Cell Reports 24(11):3072-3086.
4. Trost N, Rempel E, Ermakove O, Tamirisa S, Parcalabescu, Boutros M, Lohmann JU and Lohmann I (2018). WEADE: A workflow for enrichment analysis and data
exploration. PLoS One 13(9):e0204016.