ingrid.lohmann@cos.uni-heidelberg.de

Ingrid Lohmann, PI

Hox and me

My love story started 17 years ago in San Diego, when I first discovered Hox genes and Drosophila. Ever since I am fascinated by them and will not stop until I have hunted them down and understand all their secrets. I have to admit though that I sometimes wanted to abandon them, but they are way too cool!

Favourite techniques in Drosophila

I sit in my office, write papers and grants, no more fly pushing but one day I want to do INTACT, ChIP, dissect testes ... I love in situs, when you develop the colour and all of a sudden you see the pattern of expression of your currently favourite gene, fascinating!! And I would love to learn how to do cool bioinformatics analyses ;)

Preferred Marker / Balancer

My preferred markers are intelligence, persistence, coolness, persuasiveness, friendliness ....

What type of person am I?

early bird, intensive thinker, multi performer

How do I spend incubation times?

Well, I prefer a cup of coffee when I have to wait and I like to listen to cool music!

My CV

Click here

julie.carnesecchi@cos.uni-heidelberg.de

Julie Carnesecchi, Postdoc

Hox and me

My story begins in Lyon (France), where I discovered the force of transcriptional complexes and began to study them. Since then, I decided to become a complex hunter. Frustrated to work on a limited environment (cells), I decided to explore new horizons in Drosophila. Knowing Hox factors thanks to my PhD study environment, we spontaneously chose each other to explore the transcriptional dynamic of development. Using the chromatin as a natural landscape, we are hunting and studying complexes to understand their power.

Favourite techniques in Drosophila

Affinity purification, ChIP, everything based on acrylamide gels

Preferred Marker / Balancer

TM3, I like short hair
the marker white for transgenic, to have lovely shiny eyes with the homozygous version

What type of person am I?

early bird, intensive thinker, multi performer, male chaser (on Friday), virgin collector (every day)

How do I spend incubation times?

4-5 minutes are perfect for a coffee, longer times for bibliography!

srividya.tamirisa@cos.uni-heidelberg.de

Srividya Tamirisa, Postdoc

Hox and me

I was introduced to the world of Hox as a master student, where we identified the role Ubx in haltere specification and then I returned to a Hox lab for my postdoc. I currently work on the regulation of stem cell behaviour in the Drosophila testis.

Favourite techniques in Drosophila

Immunostainings, because I like to have some colour in my life

Preferred Marker / Balancer

Tubby

What type of person am I?

multi performer, fly kisser/matchmaker, male chaser

katrin.domsch@cos.uni-heidelberg.de

Katrin Domsch, Postdoc

Hox and me

I have a short and intensive relationship with a Hox gene named Ubx. It’s not really long but with a lot of passion. We met on the mesodermal level during embryogenesis and maybe our relationship will go on and through the larval stages. Since you, my dear, are involved in mesodermal and neuronal matching I will try to chase you down to your hiding or location in your chromatin home.

Favourite techniques in Drosophila

Ubx & TM1 staining during late embryogenic stages, that shows a whole and beautiful muscle pattern (red) with little Ubx positive nuclei (green)

Preferred Marker / Balancer

TM6, Sb, Dfd-lacZ

What type of person am I?

intensive thinker, late starter, fly kisser

My preferred breakfast

A little Rosinenbrötchen (little roll with raisins) a day will take all the stress away!

My project and my CV

Click here

pedro.pinto@cos.uni-heidelberg.de

Pedro Pinto, Postdoc

Hox and me

I am a Biochemist by training and, as a Biochemist, I like proteins and how they work and regulate complex processes. During my PhD, I studied how alternative polyadenylation of mRNAs regulate gene expression in Drosophila. Although my studies were mostly focused at the mechanistic level, by the end of my PhD I loved the little fly as a model organism and I wanted to study gene regulation during development. Therefore, I changed the field of my research, and focused on gene regulation by Hox proteins during the Drosophila embryogenesis, studying how these transcription factors regulate specific cis-Regulatory Modules (CRMs) in a spatial and temporal manner. I am interested on how these master genes activate their specific targets in a domain specific manner to establish and regulate complex morphogenetic networks.

Favourite techniques in Drosophila

generating transgenes (love molecular biology!!), immunostaining, Drosophila genetics

Preferred Marker / Balancer

Curly rocks!!! And of course CyO Wg-Z. I am also fond of TM6B … love that humeral marker (Irony)!!!!

What type of person am I?

intensive thinker, multi performer, fly kisser/matchmaker, male chaser, virgin collector, like to play with DNA molecules

How do I spend incubation times?

4-5 minutes are perfect for a coffee, longer times for bibliography!

jessica.velten@cos.uni-heidelberg.de

Jessica Velten, PhD Student

Favourite techniques in Drosophila

classical fly genetics

Preferred Marker / Balancer

Tubby

What type of person am I?

intensive thinker, multi performer, fly kisser/matchmaker, virgin collector

How do I spend incubation times?

collecting virgins

sebastian.sorge@cos.uni-heidelberg.de

Sebastian Sorge, PhD Student

Hox and me

When I joined Ingrid’s lab a long time ago to work on the transcriptional regulation by Deformed, I was fascinated by transcription factors and the Hox class in particular. After my master thesis I realised that Hox genes aren’t as special as I thought and switched to my current, non-Hox topic.

Favourite techniques in Drosophila

Most of my work relies on crosses to study genetic interactions, with the readout being adult eye or larval eye disc morphology/size/patterning.

Preferred Marker / Balancer

CyO-Tb-RFP

What type of person am I?

intensive thinker, virgin collector

How do I spend incubation times?

looking at the ceiling

nils.trost@stud.uni-heidelberg.de

Nils Trost, Master Student

Hox and me

I'm not monogamous when it comes to genes. Since I started my second semester of Bachelors, it became clear to me that I have a fascination for all of them, the more the better. That's when I got into bioinformatics. Juggling sequences, GO terms, bits and pixels has become my favourite pastime.

Favourite techniques in bioinformatics

Python, R, sequence analysis, GO term analysis, image analysis

What type of person am I?

Owl, intensive thinker, abyss starer

How do I spend computing times?

Drinking a glass of water and turning bugs into features

My website

Click here

petra.kaspar@cos.uni-heidelberg.de

Petra Kaspar, Lab Manager

Hox and me

It was a series of coincidences that led me to the Hox field. Towards the end of my studies, being still young and unexperienced, I was shanghaied by a group of harmless looking fly addicted people who made me work on Drosophila homeobox transcription factors night and day. After a couple of years, I managed to escape, but apparently I had not learned from this, because Ingrid succeeded in luring me into her lab by offering me the reign over her Hox kingdom. And here I am this very day, annoying my colleagues with nasty rules and trapping careless students that are as unexperienced as I once was…

Favourite techniques in Drosophila

Generation of transgenic flies, antibody staining, in situ hybridization.

Preferred Marker / Balancer

Brd, CyO

What type of person am I?

early bird, fly kisser/matchmaker

Time spent in the fly room

Unfortunately, not so much these days, because I am too busy thinking of new chicanery for my colleagues. But whenever I find the time, I visit my little stock collection and stroke the flies that need special care.

bernhard.glass@cos.uni-heidelberg.de

Bernhard Glaß, Technical Assistant

Hox and me

I came to the lab just a couple of years ago but I am now known as the "Fliegenkoch", since I prepare the food for all fly groups at COS. Other than that, I am responsible for the stock collection and for making the ladies in the cleaning kitchen happy.

Favourite techniques in Drosophila

I prefer to flip the flies :)

Preferred Marker / Balancer

any Balancer is fine, I have a hard time to recognize them.

What type of person am I?

early bird

How do I spend incubation time

That is my secret!

justyna.lisges@cos.uni-heidelberg.de

Justyna Lisges, Secretary

Hox and me

My story begins already a couple of years ago, when the group settled down in Heidelberg. But actually, I am not interested in Hox or flies, I have no clue about fly pushing or genetics! I take care of everything that is not related to science, my terrain is the administrative side of the Lohmann lab!

What type of person am I?

early bird, intensive thinker, multi performer

My preferred breakfast?

a cup of coffee sipped in silence for a few minutes

Still water or gas?

still water

Former Lab Members

Postdocs:
Fani Papagiannouli: Research Fellow, Margaret Fuller lab, Stanford University, USA
Maria Polychronidou: Editor "Molecular Systems Biology", Heidelberg, Germany
PhD Students:
Jana Friedrich: Postdoc, Prieto-Godino Lab, Francis Crick Institute, London, UK
Daniela Bezdan: Research Associate, Weill Cornell Medicine, New York, USA
Aurelia L. Boy: Graduiertenakademie, University of Tübingen, Germany
Nati Ha: Postdoc, DKFZ, Benedikt Brors lab, Heidelberg, Germany
Stephanie D. Hueber: Scientific Staff, University of Konstanz, Germany
Petra Stöbe: Scientific Staff, CeGat, Tübingen, Germany
Zongzhao Zhai: Postdoc, EPFL, Bruno Lemaitre lab, Lausanne, Switzerland
Master Students:
Maike Graf
Christian Altbürger: PhD student, Wolfgang Driever lab, University of Freiburg, Germany
Fatmire Bujupi: PhD student, Peter Kramer lab, DKFZ, Heidelberg, Germany
Janin Grajcarek: Fellow Senior Associate, McKinsey
Andreas Hunczek: Research Fellow, Forschungszentrum Kinderkrebs-Zentrum-Hamburg, Germany
Juliane Mundorf: PhD student, Mirka Uhlirova lab, University of Cologne, Germany
Michael Piechotta: MPI for Biology of Ageing, Cologne, Germany
Jenny Rätzer: PhD student, Mathias Treier lab, MDC, Berlin, Germany
Naima Ruhland: PhD student, Steffen Lemke lab, Heidelberg University, Germany
Martin Schaefer: Postdoc, CRG, Luis Serrano lab, Barcelona, Spain
Lisa Schardt: PhD student, Petra Boukamp lab, DKFZ, Heidelberg, Germany
Sokrates Stein: Group leader, SNF Ambizione, Lausanne, Switzerland
Jelena Vulic
Bachelor Students:
Natascha Bartsch: Master student "Developmental and Stem Cell Biology", Heidelberg University, Germany
Martina Blank: Biologist, Federal University of Santa Catarina, Brazil
Vanessa Disela: Master student "Molecular Biosciences", Heidelberg University, Germany
Pauline Jeckel: Master student "Neurowissenschaften", University of Tübingen,Germany
Simone Mumbauer: PhD student, Hamaratoglu Dion lab, University of Lausanne, Switzerland
Katrin Schaak: Postdoc, MRC Center for Regenerative Medicine, Edinburgh, Great Britain
Michaela Wölk: Master student "Molecular Biosciences", Heidelberg University, Germany
Internship Students:
Samantha Brunel: Paris, France
Natalie Grace Schulz: Boston, USA